The reference site for Terbinafine

Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat ringworm, pityriasis versicolor, and fungal nail infections.

WHAT IS Terbinafine?

This new site is dedicated exclusively to terbinafine.

It provides you with the most extensive product information and up-to-date resources regarding this medication, including related news articles, medical studies, an image library and all the necessary information on dosage and side effects.

Whether you are an average consumer or a pharma industry professional, you can now find out everything you need to know about terbinafine on this reference site, as well as take part in our open discussion forum by sharing your own knowledge and experience with people who are using this medication.

This unique site will also provide you with inside industry news on which companies or organizations are playing an important part in its research, development, production and promotion. It is your one-stop site for a total terbinafine experience!

 

Brand Name(s): Lamisil
CAS nº: 91161-71-6
(ter-bin-a-feen)

 

Product Info

The sections below will provide you with more specific information and guidelines related to terbinafine and its correct use. Please read them carefully.

FDA Information

Topical terbinafine was approved by the FDA in 1993. Terbinafine oral tablets were approved in 1996.

Why is this medication prescribed?

Terbinafine is used to treat fungal infections of the toenail and fingernail. Terbinafine is in a class of medications called antifungals. It is taken by mouth or applied to the skin.

This medicine acts by interfering with the ability of fungi to make chemicals called sterols that are an important part of the membrane that surrounds fungal cells and holds them together. This weakens the cell membrane.

Oral terbinafine is more effective for treating fungal nail infections than griseofulvin (Fulvicin; Gris-Peg) and itraconazole (Sporanox), two other antifungal agents used for treating fungal nail infections.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Usage-

Apply enough terbinafine cream to cover the affected and surrounding skin areas and rub in gently.

Apply enough terbinafine solution to wet and cover the affected and surrounding skin areas. Allow it to dry.

Keep this medicine away from the eyes, nose, mouth, and other mucous membranes. The solution may be especially irritating to the eyes.

Terbinafine spray solution contains alcohol and should not be applied to the face.

Do not apply an occlusive dressing (airtight covering, such as a tight bandage or plastic kitchen wrap) over this medicine unless you have been directed to do so by your doctor.

Dosing-

The dose of terbinafine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of terbinafine. If your dose is different, do not change it unless your doctor tells you to do so.

The number of doses you use each day, the time allowed between doses, and the length of time you use the medicine depend on the medical problem for which you are using terbinafine.

For topical dosage form (cream):


For cutaneous candidiasis:

Adults—Use one or two times a day for seven to fourteen days.
Children—Use and dose must be determined by your doctor.

For tinea corporis or tinea cruris:

Adults and children 12 years of age and older—Use one or two times a day for seven to twenty-eight days.
Infants and children younger than 12 years of age—Use and dose must be determined by your doctor.

For tinea pedis (interdigital):
Adults and children 12 years of age and older—Use two times a day for seven to twenty-eight days.
Infants and children younger than 12 years of age—Use and dose must be determined by your doctor.

For tinea pedis (plantar):

Adults and children 12 years of age and older—Use two times a day for fourteen days.
Infants and children younger than 12 years of age—Use and dose must be determined by your doctor.

For tinea versicolor:
Adults—Use one or two times a day for fourteen days.
Children—Use and dose must be determined by your doctor.


For topical dosage form (spray solution):

For tinea corporis or tinea cruris:
Adults—Use once a day for seven days.
Children—Use and dose must be determined by your doctor.

For tinea pedis or tinea versicolor:

Adults—Use two times a day for seven days.
Children—Use and dose must be determined by your doctor.

To help clear up your infection completely, it is very important that you keep using terbinafine for the full time of treatment , even if your symptoms begin to clear up after a few days. Since fungus infections may be very slow to clear up, you may have to continue using this medicine every day for several weeks or more. If you stop using this medicine too soon, your symptoms may return.

What special precautions should I follow?

BEFORE TAKING TERBINAFINE:

Tell your doctor if you are taking any of the following medicines: cimetidine (Tagamet, Tagamet HB).; rifampin (Rifadin, Rimactane); or cyclosporine (Sandimmune, Neoral). You may not be able to take terbinafine, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Do not take terbinafine without first talking to your doctor if you have ever had an allergic reaction to it, liver disease, kidney disease, problems with your immune system, or blood problems. You may not be able to take terbinafine, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

Terbinafine is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take terbinafine without first talking to your doctor if you are pregnant.

Terbinafine passes into breast milk and may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

Avoid alcohol or use it in moderation while taking terbinafine. Alcohol and terbinafine can both affect the liver.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

What side effects can this medication cause?

Possible side effects from terbinafine include:

diarrhea
abdominal pain
hives
itching
Increases in liver enzymes
altered taste sensation

Tell your doctor if any of these symptoms are severe or do not go away:

nausea, upset stomach, or heartburn
diarrhea or flatulence
headache
taste disturbances or a loss of taste

If you experience any of the following symptoms, call your doctor immediately:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives)
a rash
changes in vision
blood problems (detected by blood tests)

In rare cases, terbinafine has caused severe liver damage, sometimes resulting in liver transplant or death. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, itching, dark urine, or clay colored stools. These symptoms may be early signs of liver damage.Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

drowsiness
poor coordination
shortness of breath
abdominal pain
frequent urination
rash
headache

Product Images

PICTURES OF TERBINAFINE PILLS

Below you will find images and specific information on the principal types of terbinafine that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: LAMISIL®
Strength(s): 1%
Imprint: Lamisil Topical Spray
Manufacturer: NOVARTIS PHARMACEUTICALS

Name: LAMISIL®
Strength(s): 1%
Imprint: LAMISIL
Manufacturer: NOVARTIS CONSUMER HEALTH INC

Name: LAMISIL®
Strength(s): 250 MG
Imprint: LAMISIL 250
Manufacturer: NOVARTIS

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